Premier Glucose Manager™
Advanced Dual-Action Blood Sugar & Metabolic Support*
Premier Glucose Manager™ by Premier Research Labs is a practitioner-grade formula designed to support healthy blood sugar balance, metabolic function, and insulin sensitivity.*
This advanced formula combines two clinically researched ingredients at evidence-based doses to help regulate glucose metabolism at both the digestive and cellular levels.*
Each capsule delivers:
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GlucoVantage® Dihydroberberine – 100 mg
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Reducose® Mulberry Leaf Extract – 250 mg (standardized to 12.5 mg DNJ)
Together, these ingredients support balanced blood sugar responses before and after meals, helping maintain healthy glucose levels across the entire glycemic cycle.*
A Complete Approach to Blood Sugar Support
Most glucose supplements focus on only one metabolic pathway. Premier Glucose Manager™ works differently by addressing two key mechanisms of blood sugar regulation:
1. Carbohydrate digestion and absorption
2. Cellular glucose utilization and insulin signaling
This dual-action strategy helps moderate post-meal glucose spikes while promoting efficient cellular energy metabolism.*
Clinically Validated Ingredients
GlucoVantage® Dihydroberberine
Enhanced Berberine Technology for Superior Bioavailability*
GlucoVantage® is an advanced form of berberine known as dihydroberberine (DHB). This hydrogenated derivative provides up to 5× greater bioavailability than traditional berberine, allowing for effective metabolic support at lower doses with improved tolerance.*
How it works
Dihydroberberine activates AMPK, often called the body’s master metabolic regulator. AMPK activation helps support insulin sensitivity, healthy glucose uptake, and mitochondrial energy production in muscle and liver tissue.*
With a half-life of approximately 4–6 hours, DHB provides sustained metabolic support throughout the day.*
Benefits
• Supports insulin sensitivity and glucose metabolism*
• Helps maintain healthy fasting blood sugar levels*
• Promotes healthy lipid metabolism*
• Supports mitochondrial energy production*
• More microbiome-friendly than traditional berberine*
Reducose® Mulberry Leaf Extract
Clinically Studied Support for Post-Meal Glucose Balance*
Reducose® is a patented mulberry leaf extract standardized to 5% 1-Deoxynojirimycin (DNJ), delivering 12.5 mg DNJ per serving — up to 50× more DNJ than standard mulberry extracts.*
This ingredient has been studied in multiple human clinical trials for its ability to support healthy glucose levels following carbohydrate consumption.*
How it works
DNJ naturally inhibits alpha-glucosidase enzymes in the small intestine. This slows the breakdown of carbohydrates into simple sugars, helping smooth post-meal glucose responses and reduce insulin demand.*
Benefits
• Supports balanced blood sugar after meals*
• Helps moderate post-meal glucose spikes*
• Supports healthy insulin response*
• Helps convert high-glycemic foods into lower-glycemic equivalents*
• Water-extracted with no harsh solvents*
Clean, Practitioner-Grade Formula
Premier Glucose Manager™ is formulated to meet the highest professional standards.
✔ No synthetic additives
✔ No harsh solvents
✔ No unnecessary fillers or excipients
✔ Practitioner-quality ingredients
Every batch is rigorously tested for identity, purity, potency, and microbiological safety to ensure uncompromised quality.
Important Safety Information
If you are currently taking medications for blood sugar regulation, consult your healthcare provider before using this product, as it may enhance glucose-lowering effects.
Dihydroberberine may interact with medications metabolized by CYP450 enzymes or P-glycoprotein transporters.
Not recommended during pregnancy or lactation. Keep out of reach of children.
This formula is generally well tolerated. The enhanced bioavailability of GlucoVantage® DHB helps minimize the gastrointestinal discomfort often associated with traditional berberine supplements.